What STD stays with you for life? The other 4 are viral infections which are incurable: hepatitis B, herpes simplex virus (HSV or herpes), HIV and human papillomavirus (HPV). STIs are spread predominantly by sexual contact, including vaginal, anal and oral sex.
What is the most threatening STD? The most dangerous viral STD is human immunodeficiency virus (HIV), which leads to AIDS.
What STD is known as the silent? Some refer to chlamydia as a “silent” infection. This is because most people with the infection have no symptoms or abnormal physical exam findings.
Which STD is most commonly reported? Chlamydia is the most commonly reported STD, with over 1.8 MILLION CASES reported in 2019. Young women (ages 15-24) account for 43% of reported cases and face the most severe consequences of an undiagnosed infection.